Question 14

(Multiple Choice)

Which of the following statements best describes the difference between low-affinity integrins and high-affinity integrins?


A)Many integrins can exist in two conformations: a low-affinity (bent)conformation and a high-affinity (straight)conformation.
B)Dissociation of the αβ heterodimer converts many integrins from the low-affinity to the high-affinity state.
C)Association of the αβ heterodimer converts many integrins from the low-affinity to the high-affinity state.
D)Proteolytic cleavage of the C-terminal tails of the two subunits converts many integrins from the low-affinity to the high-affinity state.

Answer