During G₁,prereplication Complexes

Question

During G₁,prereplication complexes:
A)are phosphorylated by B-type cyclin-CDKs.
B)are phosphorylated by DDK.
C)bind to ORC.
D)all of the above

Accepted Answer

During G1 phase, prereplication complexes bind to the origin recognition complex (ORC), which is responsible for initiating DNA replication. Phosphorylation of the complex by B-type cyclin-CDKs and DDK occurs later in the cell cycle during S phase, after the formation of the ORC has already occurred. Therefore, option C is the best choice.