Human Genes/proteins That Regulate the Cell Cycle are Most Easily

Question

Human genes/proteins that regulate the cell cycle are most easily isolated by:
A)biochemical purification.
B)complementation of Xenopus mutants.
C)complementation of yeast mutants.
D)positional cloning.

Accepted Answer

Complementation of yeast mutants is the most effective way to isolate human genes/proteins that regulate the cell cycle. This is because yeast is a simple eukaryotic organism and their cell cycle mechanisms are highly conserved with humans. Therefore, when a human gene/protein replaces a mutated yeast gene/protein, it can restore the normal cell cycle function, providing a powerful tool for gene/protein identification.