Human Leucocyte Antigen (HLA)proteins Are

Question

Human leucocyte antigen (HLA)proteins are
A)found only on leucocytes.
B)coded for by the major histocompatibility complex.
C)produced by the immune system following organ transplantation.
D)the main targets in autoimmune responses.
E)completely different in all individuals.

Accepted Answer

HLA proteins are coded for by genes located in the major histocompatibility complex (MHC) of chromosome 6 in humans. These proteins are expressed by almost all nucleated cells as well as on some platelets, and play a crucial role in the immune system by presenting antigens to T cells. Matching of HLA proteins is important for organ and bone marrow transplantation to prevent rejection.