Which of the Following Statements is TRUE

Question

Which of the following statements is TRUE?
A)The presence of fever is often,but not always,an indication of infection.
B)Fever is produced by endogenous chemicals which act on the hypothalamus.
C)Exogenous pyrogens are products of some infectious organisms.
D)Intravenous fluids labelled 'pyrogen-free' do not contain dead bacteria.
E)All of the above.

Accepted Answer

All of the statements are true. Fever can be a signal of infection, but can also be caused by other factors such as inflammation and certain medications. Endogenous chemicals, such as cytokines, can trigger fever by signaling the hypothalamus to raise the body's temperature. Exogenous pyrogens are substances produced by infectious organisms, such as lipopolysaccharides (LPS) found in Gram-negative bacteria. Intravenous fluids labelled as pyrogen-free indicate that they do not contain any substances that could cause fever, such as dead bacteria.