Quinolones Kill Bacteria by What Mechanism

Question

Quinolones kill bacteria by what mechanism?
A) It inhibits DNA gyrase.
B) It inhibits DNA compaction.
C) It inhibits DNA replication.
D) All of these choices are correct.

Accepted Answer

Quinolones inhibit DNA gyrase, an essential enzyme for bacterial DNA replication and repair. Without functional DNA gyrase, the bacterial DNA becomes damaged and the cell eventually dies.