What is a Disease Associated with Extranuclear Inheritance

Question

What is a disease associated with extranuclear inheritance?
A) Angelman Syndrome
B) Prader-Willi Syndrome
C) LHON
D) Muscular Dystrophy

Accepted Answer

LHON (Leber's hereditary optic neuropathy) is a disease associated with extranuclear inheritance, meaning it is caused by mutations in mitochondrial DNA, which is inherited from the mother. The other three choices (Angelman Syndrome, Prader-Willi Syndrome, and Muscular Dystrophy) are all caused by mutations in genes located in the nucleus and inherited in a Mendelian manner.