Which of the Following Statements About Cytotoxic Hypersensitivity is Correct

Question

Which of the following statements about cytotoxic hypersensitivity is correct
A)Normally a person's serum has IgM against the antigens on their own red blood cells.
B)Adverse transfusion reactions are no longer a problem because transfusions rarely occur.
C)Hemolytic disease of the newborn cannot be prevented.
D)Sensitization to Rh antigens can occur during delivery,miscarriage or abortion.

Accepted Answer

Sensitization to Rh antigens can occur during delivery, miscarriage, or abortion, leading to the production of IgG antibodies against Rh antigens in the mother's serum. If a subsequent pregnancy involves an Rh-positive fetus, the mother's Rh antibodies can cross the placenta and cause hemolytic disease of the newborn. Adequate anti-Rh immunoglobulin given to the mother can prevent sensitization and subsequent hemolytic disease of the newborn. The other statements are incorrect.