Polypeptide Antibiotics That Act as Detergents and Distort Bacterial Cellular

Question

Polypeptide antibiotics that act as detergents and distort bacterial cellular membranes do so by:
A)acting as antimetabolites
B)inhibition of cell wall synthesis
C)disruption of cell membrane integrity
D)inhibition of nucleic acid synthesis

Accepted Answer

Polypeptide antibiotics that act as detergents and distort bacterial cellular membranes disrupt the cell membrane integrity, leading to leakage of cellular contents and eventually cell death. Examples of such antibiotics include polymyxins and colistin. They do not act as antimetabolites, inhibitors of cell wall or nucleic acid synthesis.