Which of the Following Viruses Has Been Used to Express

Question

Which of the following viruses has been used to express large proteins in cultured cells?
A) Adenovirus.
B) Baculovirus
C) Herpes simplex virus
D) Both adenovirus and baculovirus
E) Both adenovirus and herpes simplex virus

Accepted Answer

Both adenovirus and baculovirus have been used to express large proteins in cultured cells. Adenovirus can efficiently deliver genes into many types of cells, including non-dividing cells, and has a high transduction efficiency. Baculovirus, on the other hand, is a commonly used virus for protein expression in insect cells, and can express very large proteins up to 200 kDa.