The E1A protein from adenovirus indirectly stabilizes the cellular p53 protein.Why is this potentially a problem for the virus?

A) This will activate the adaptive immune response against virally infected cells.
B) This will initiate the RNAi pathway, which leads to degradation of viral RNA.
C) This will induce the apoptosis pathway, which leads to cell death.
D) The virus requires active p53 protein to activate viral genes.
E) The virus does not use p53, so this is not a problem at all.