Question 1

(Multiple Choice)

During the cell cycle in an uninfected cell, the cellular protein Rb represses S phase genes by doing which of the following?


A) Localizes histone deacetylase to E2F inducible genes.
B) Binds to the adenovirus E1A protein and releases E2F.
C) Prevents binding of the cellular RNA polymerase II to E2F inducible genes.
D) Binds and phosphorylates the cyclin dependent kinase.
E) Prevents the binding of E2F to the promoters of S phase genes.

Answer

A