Most viruses must exit the endosome before it fuses with a lysosome.Why?
A) Their envelope will not fuse easily with the lysosomal membrane.
B) To avoid the very low pH in the lysosome, which causes destructive conformational changes.
C) To avoid being degraded by lysosomal proteases and nucleases.
D) To enhance their movement towards the nucleus of the cell.
E) The pH of the lysosome is too high to induce membrane fusion.