Virus Particles Can Be Visualized with Which of the Following

Question

Virus particles can be visualized with which of the following?
A) negative staining of virions with electron microscopy
B) negative staining of virions with x-ray diffraction
C) negative staining of thin sections of infected cells with electron microscopy
D) positive staining in cryoelectron microscopy
E) positive staining of infected cells with x-ray diffraction

Accepted Answer

Negative staining of virions with electron microscopy is a common technique used to visualize virus particles. The negative staining method allows visualization of the virus particle morphology and size by creating a contrast between the background and the specimen. This technique involves staining the specimen with a heavy metal salt, which forms a negative image of the virus particle. X-ray diffraction is not commonly used for visualization of virus particles, and positive staining with cryoelectron microscopy or x-ray diffraction is not commonly used. Negative staining of infected cells with electron microscopy is also a method used to visualize virus particles, but it is less common than negative staining of virions.