What is the advantage that heterozygotes of the sickle cell gene have over people who are not carriers?

A) Carriers of the sickle cell allele are resistant to developing Huntington disease.
B) Carriers of the sickle cell allele are resistant to malaria.
C) Carriers of the sickle cell allele are resistant to Tay-Sachs.
D) Carriers are more likely to live longer than non-carriers.
E) Carriers of the sickle cell allele are resistant to cystic fibrosis.