Preimplantation Genetic Diagnosis (PGD)

Question

Preimplantation genetic diagnosis (PGD)
A) can be used to detect genetic abnormalities before the oocyte is fertilized.
B) can be used to detect genetic abnormalities before the embryo is implanted in the mother.
C) requires analysis of all of the blastomeres in the early embryo.
D) takes place after in vitro fertilization.
E) depends on direct microscopic analysis of embryonic cells.

Accepted Answer

Preimplantation genetic diagnosis (PGD) is a technique for genetic testing of embryos. It involves analyzing the genetic material of embryos before they are implanted in the mother, usually after in vitro fertilization. PGD allows for the detection of genetic abnormalities before the embryo is implanted, so that only unaffected embryos are selected for transfer. It does not require analysis of all of the blastomeres in the early embryo, and can be performed using various methods such as FISH (fluorescent in situ hybridization), PCR (polymerase chain reaction), or next-generation sequencing.