Which of These Statements Does NOT Apply to Endogenous Pyrogen

Question

Which of these statements does NOT apply to endogenous pyrogen
A)It is an acute-phase protein produced by the liver.
B)It is secreted by phagocytes at a site of inflammation.
C)It induces the development of fever.
D)It is the same as or closely related to leukocyte endogenous mediator and interleukin 1.

Accepted Answer

Endogenous pyrogen is not an acute-phase protein produced by the liver. It is produced by activated immune cells such as phagocytes and induces fever by acting on the hypothalamus. It is closely related to leukocyte endogenous mediator and interleukin 1.