Why Do Steroids Take So Long to Generate Change When

Question

Why do steroids take so long to generate change when they bind to intracellular receptors?
A)The intracellular receptors have very slow kinetics.
B)The bound receptors affect gene transcription rates.
C)The steroid receptor complex activates signal transduction pathways.
D)The steroid receptor complex must then exit the cell to exert its effects.

Accepted Answer

Steroids bind to intracellular receptors and form a receptor-hormone complex that regulates gene expression. This process requires the transcription of new proteins, which takes time to generate change. Thus, the bound receptors affect gene transcription rates and this is why it takes time for steroids to generate change.