Virulence Mechanisms Possessed by Plasmodium Species Include the Ability

Question

Virulence mechanisms possessed by Plasmodium species include the ability:
A)To facilitate pyrimidine nucleoside precursor uptake
B)To facilitate purine nucleoside precursor uptake
C)To add acetyl groups to histone proteins
D)To inhibit the action of RNA polymerase II
E)To remove acetyl groups present on histone proteins

Accepted Answer

Plasmodium species require purine nucleoside precursors for DNA synthesis, and have developed virulence mechanisms to facilitate their uptake from the host. This includes the expression of specific transporters for purine nucleosides, such as the equilibrative nucleoside transporter 1 (ENT1) and the purine nucleoside transporter (PfNT1).