How Does the Polio Virus Cause Cell Death

Question

How does the polio virus cause cell death?
A)By preventing host cell protein synthesis.
B)Through destruction of the cytoplasmic membrane.
C)By inhibition of DNA replication.
D)Through destruction of the nuclear membrane.
E)By repression of host cell transcription.

Accepted Answer

The polio virus inhibits the host cell's protein synthesis by cleaving a specific protein called eIF4G, which is essential for the translation of mRNA into protein. This inhibition ultimately leads to cell death.