What is the Correct Activation Sequence for CD4⁺ Cells

Question

What is the correct activation sequence for CD4⁺ cells?
A)Stimulation of B-cells for antibody production,response to MHC II-peptide complexes
B)response to MHC II-peptide complexes,differentiation into TH and memory cells
C)The cytotoxic killing of infected cells,production of Interleukin-2
D)response to MHC II-peptide complexes,production of Interleukin-2
E)Stimulation of dendritic cells,response to MHC II-peptide complexes

Accepted Answer

The correct activation sequence for CD4⁺ cells is response to MHC II-peptide complexes, followed by production of Interleukin-2. This cytokine is involved in the differentiation of CD4⁺ cells into T helper cells and memory cells. Option D is the only choice that includes both of these steps in the correct order.