A Sensitized B Cell Typically is Not Activated Until

Question

A sensitized B cell typically is not activated until
A) it binds a helper T cell that releases cytokines.
B) it binds a cytotoxic T cell.
C) memory B cells have been cloned.
D) it has cloned plasma cells.
E) antibodies have been produced.

Accepted Answer

A sensitized B cell depends on the binding of a helper T cell that releases cytokines to become fully activated. This interaction is necessary for the B cell to differentiate into plasma cells and produce antibodies. Without the help of a helper T cell, the sensitized B cell cannot activate itself. Therefore, option A is the correct answer.