B Cells are Primarily Activated by the Activities Of

Question

B cells are primarily activated by the activities of
A) antigens.
B) antibodies.
C) helper T cells.
D) macrophages.
E) plasma cells.

Accepted Answer

Helper T cells play a major role in activating B cells by recognizing the antigen presented on the surface of antigen-presenting cells (such as macrophages) and releasing cytokines that stimulate B cell proliferation and differentiation into antibody-secreting plasma cells. Antigens themselves may directly bind to B cell receptors and activate them, but usually require the help of helper T cells for full activation. Antibodies are produced by B cells and are not involved in their activation. Plasma cells are differentiated B cells that secrete antibodies. Macrophages can present antigens to helper T cells, but do not directly activate B cells.