The Release of Endogenous Pyrogen (Or Interleukin-1) by Active Macrophages

Question

The release of endogenous pyrogen (or interleukin-1) by active macrophages would
A) cause inflammation.
B) produce a fever.
C) activate complement.
D) opsonize pathogens.
E) activate antibodies.

Accepted Answer

Endogenous pyrogen or interleukin-1 is a cytokine released by active macrophages that acts on the hypothalamus to cause an increase in body temperature, resulting in a fever.