Intracellular Calcium Stores Open in Response to Intracellular Activation Of

Question

Intracellular calcium stores open in response to intracellular activation of
A) protein kinase C, diacylglycerol, and inositol triphosphate.
B) calmodulin.
C) leukotrienes.
D) adenylate cyclase.
E) phosphodiesterase, adenylate cyclase, and prostacyclins.

Accepted Answer

Intracellular calcium stores are typically opened in response to intracellular activation of protein kinase C, diacylglycerol, and inositol triphosphate. These signaling molecules can trigger the release of calcium from intracellular stores such as the endoplasmic reticulum. Calmodulin is a calcium-binding protein that is involved in downstream signaling pathways once calcium is released, but it does not initiate release on its own. Leukotrienes are lipid signaling molecules that are involved in inflammation and immune response but are not directly involved in calcium release. Adenylate cyclase and phosphodiesterase are enzymes involved in the cyclic AMP signaling pathway, while prostacyclins are lipid signaling molecules involved in vasodilation and platelet aggregation, but none of these are directly involved in calcium release.