Tom suffers from hypertension (high blood pressure). Which of the following might help deal with his problem?

A) a drug that blocks alpha-1 receptors in smooth muscle
B) a drug that blocks alpha-2 receptors in adipose tissue
C) a drug that increases cAMP levels in cardiac muscle tissue
D) a drug that blocks beta receptors in cardiac muscle tissue
E) a drug that blocks alpha-1 receptors in smooth muscle and blocks beta receptors in cardiac muscle tissue