The Release of GABA and Subsequent Inhibition of Voltage Gated

Question

The release of GABA and subsequent inhibition of voltage gated calcium channels is associated with
A) presynaptic inhibition.
B) presynaptic facilitation.
C) spatial summation.
D) temporal summation.
E) spatial facilitation.

Accepted Answer

The release of GABA is associated with presynaptic inhibition, which occurs when a neuron releases an inhibitory neurotransmitter that decreases the release of neurotransmitters from presynaptic terminals. The subsequent inhibition of voltage gated calcium channels reduces the likelihood of action potential generation in the presynaptic neuron, leading to decreased neurotransmitter release.