IPSPs (Inhibitory Postsynaptic Potentials)

Question

IPSPs (inhibitory postsynaptic potentials)
A) are local depolarizations.
B) are local hyperpolarizations.
C) increase membrane permeability to sodium ions.
D) block the efflux of potassium ions.
E) block the efflux of calcium ions.

Accepted Answer

IPSPs are inhibitory because they cause a local hyperpolarization, making it more difficult for the postsynaptic neuron to become depolarized and fire an action potential. This is achieved by increasing membrane permeability to potassium ions or chloride ions, causing an efflux of ions and maintaining a negative resting potential.