The Ion That Triggers the Release of Acetylcholine into the Synaptic

Question

The ion that triggers the release of acetylcholine into the synaptic cleft is
A) sodium.
B) potassium.
C) calcium.
D) chloride.
E) magnesium.

Accepted Answer

Calcium ions are responsible for triggering the release of acetylcholine into the synaptic cleft by causing vesicles containing acetylcholine to fuse with the presynaptic membrane and release their contents into the synapse. Sodium, potassium, chloride, and magnesium ions do not play a direct role in the release of acetylcholine.