Which of These Reactions Do Amino-Acyl-TRNA Synthetases Catalyze

Question

Which of these reactions do amino-acyl-tRNA synthetases catalyze?
A)specific amino acid attachment to the 3'-OH at the 3'-CCA of a specific tRNA
B)specific amino acid attachment to the 5'-OH at the 5'-CCA of a specific tRNA
C)specific tRNA with ATP to form a so-called "charged tRNA" that interacts with a specific site on mRNA
D)specific tRNA with GTP to form a so-called "charged tRNA" that interacts with a specific site on mRNA

Accepted Answer

Aminoacyl-tRNA synthetases catalyze the specific attachment of an amino acid to the 3'-OH of the 3'-CCA end of a specific tRNA. This reaction is also known as tRNA charging or aminoacylation.