Which of the Following is the Function of Phosphoribosyltransferases

Question

Which of the following is the function of phosphoribosyltransferases?
A)They are involved in the reversible reactions of purine salvage.
B)They mediate the degradation of AMP.
C)They are central to the resynthesis of nucleotides from bases in salvage reactions.
D)They mediate the degradation of IMP.

Accepted Answer

Phosphoribosyltransferases are enzymes that catalyze the transfer of a phosphoribosyl group from 5-phosphoribosyl-1-pyrophosphate (PRPP) to a base, forming a nucleoside monophosphate. This reaction is central to the resynthesis of nucleotides from bases in salvage reactions.