Which of the Following Statements is NOT Correct Regarding Cyclic

Question

Which of the following statements is NOT correct regarding cyclic sugars?
A)The a-anomer has the -OH of the anomeric carbon positioned on the opposite side of the sugar ring from the -CH₂OH.
B)The 5- and 6-membered rings are more frequently observed due to stability.
C)In a chair conformation,the predominant form has the bulkiest substituents occupying axial positions.
D)They can be formed by the intramolecular reactions to hemiacetals or hemiketals.

Accepted Answer

In a chair conformation of cyclic sugars, the predominant form has the bulkiest substituents in equatorial positions, not axial, because this arrangement minimizes steric hindrance and is therefore more stable.