A Cell Expressing Cell Surface MHC Class II, CD80/88 and Secretes

Question

A cell expressing cell surface MHC Class II, CD80/88 and secretes IL-12 is a(n)
A)Immature myeloid-derived dendritic cell
B)Mature myeloid-derived dendritic cell
C)Follicular dendritic cell
D)B cell
E)Macrophage

Accepted Answer

Immature dendritic cells at the infection site are triggered to mature and migrate to the lymph node. Immature dendritic cells have low expression of MHC Class II, but mature cells have high expression levels of both MHC Class II and CD80/88.