What Effect Does the Presence of Mullerian Inhibiting Substance Have

Question

What effect does the presence of Mullerian inhibiting substance have on fetal development?
A) development of male organs
B) development of Wolffian ducts
C) degeneration of Mullerian ducts
D) development of female organs
E) none of these

Accepted Answer

Mullerian inhibiting substance, also known as anti-Mullerian hormone (AMH), is produced by the Sertoli cells of the testes in male embryos. Its primary role is to cause the regression or degeneration of the Mullerian ducts, which in the absence of this substance would develop into female reproductive organs such as the uterus, fallopian tubes, and the upper part of the vagina.