Which of the Following Statements Below About the Activation of Fatty

Question

Which of the following statements below about the activation of fatty acids is false?
A) Activation involves the formation of a high energy thioester bond.
B) Activation is accompanied by hydrolysis of ATP to ADP and Pi.
C) Activation includes the formation of an acyl-adenylate intermediate.
D) Activation includes hydrolysis of ATP to produce AMP and PPi, with the further hydrolysis of PPito drive the reaction to completion.

Accepted Answer

The correct statement is that activation of fatty acids involves the hydrolysis of ATP to AMP and PPi (pyrophosphate), not ADP. This process is crucial for driving the reaction towards completion by the further hydrolysis of PPi.