Is the Michaelis-Menten Equation Useful When Studying Allosteric Enzymes

Question

Is the Michaelis-Menten equation useful when studying allosteric enzymes?
A) Yes
B) No
C) Only if the enzyme displays positive cooperativity.
D) Only if the enzyme displays negative cooperativity.

Accepted Answer

The Michaelis-Menten equation is specifically designed for studying enzymes that follow simple kinetics and do not exhibit any allosteric behavior. Allosteric enzymes have non-linear rate equations and do not follow the simple Michaelis-Menten kinetics. Therefore, the Michaelis-Menten equation would not be useful when studying allosteric enzymes.