The Enzyme Responsible for Converting Androgens to Estrogens Is

Question

The enzyme responsible for converting androgens to estrogens is
A) 5α-reductase.
B) TDF.
C) aromatase.
D) AMH.

Accepted Answer

The enzyme responsible for converting androgens to estrogens is aromatase. Aromatase is responsible for the conversion of testosterone to estradiol and androstenedione to estrone. 5α-reductase is responsible for converting testosterone to its more potent form, dihydrotestosterone (DHT). TDF (testis-determining factor) is a gene on the Y chromosome that is responsible for initiating male development during embryogenesis. AMH (anti-Müllerian hormone) is produced by the Sertoli cells in the testes and is responsible for inhibiting the development of the Müllerian ducts in males, which later develop into female reproductive organs.