Angiogenesis Is

Question

Angiogenesis is
A) an examination of the arteries and veins.
B) having blood drawn into a tube for tests.
C) the growth of new blood vessels.
D) surgical restructuring of the coronary arteries.
E) being able to detect a pulse in arteries.

Accepted Answer

Angiogenesis refers to the formation of new blood vessels from pre-existing ones, which is a crucial process in the growth and development of tissues and organs, as well as in wound healing, inflammation, and cancer progression. It involves the activation, proliferation, migration, and differentiation of endothelial cells, which line the inner surface of blood vessels, as well as the recruitment and integration of other cell types, such as pericytes, smooth muscle cells, and immune cells. Angiogenesis can be triggered by various factors, such as growth factors, cytokines, chemokines, extracellular matrix proteins, and hypoxia, and can be modulated by a variety of signaling pathways, such as VEGF, FGF, Notch, and Wnt. Understanding angiogenesis is important for developing novel therapies for diseases that involve either insufficient or excessive blood vessel formation, such as ischemia, diabetic retinopathy, macular degeneration, and cancer.