Each of the following statements concerning peptide hormones is True except one.Identify the exception.

A) Peptide hormones are first synthesized as prohormones.
B) Prohormones can be activated before their release via post-translational modification.
C) Peptide hormones remain in circulation for relatively short periods of time.
D) Peptide hormones in the bloodstream are always bound to carrier proteins.
E) Peptide hormones interact with receptors on the surface of their target cells.