Which of the statements about replication error and repair during DNA synthesis are true? Please select all that apply.

A) The error rate during DNA replication is approximately 100-fold higher than the error rate after proofreading
B) DNA polymerases can have 3' endonuclease activity
C) Error-prone polymerases do not have proofreading capacity
D) Base tautomerization can lead to non-Watson-Crick base pairing