Which Enzyme Separates the Strands of the DNA Double Helix

Question

Which enzyme separates the strands of the DNA double helix during replication?
A) DNA helicase
B) DNA polymerase
C) DNA ligase
D) RNA polymerase

Accepted Answer

DNA helicase is responsible for unwinding the double-stranded DNA molecule by breaking the hydrogen bonds between the complementary base pairs. This creates a replication fork, which allows DNA polymerase to synthesize new strands of DNA.