Which of the Following are Components of the Preinitiation Complex

Question

Which of the following are components of the preinitiation complex? Please select all that apply.
A) General transcription factors
B) RNA polymerase
C) Initiator elements
D) Exons
E) TFIID

Accepted Answer

The preinitiation complex is a complex of proteins bound at the core promoter prior to initiation in eukaryotes. Initiator elements and exons are DNA features, so are not considered to be part of the preinitiation complex. TFIID (a general transcription factor) binds to DNA then recruits RNA polymerase and other general factors to make the preinitiation complex.