Analysis of microbial communities by direct sequencing has numerous advantages over culture-dependent analysis. Which of the following are advantages of culture-based methods over culture-independent analysis? Please select all that apply.

A) Culture-dependent methods capture
More species than culture-independent methods
B) Cultured organisms can provide reference genomes
C) Culture-based methods are less biased than direct sequencing
D) Cultivation is better at identifying low-abundance organisms than direct sequencing