Which genotype would have an advantage if a recessive allele changed cellular proteins that led to circulatory problems and premature death?

A) Any homozygous individual will always have an advantage over any heterozygous individual.
B) Any heterozygous individual will always have an advantage over any homozygous individual.
C) Any homozygous dominant individual will always have a disadvantage compared to any heterozygous individual.
D) Any heterozygous individual will have an advantage over any homozygous recessive individual.