What is Meant by the "Multiple Hit" Model of Cancer

Question

What is meant by the "multiple hit" model of cancer?
A) Most cancer-causing mutations are passed on to future generations.
B) Most cancers occur in many different tissues simultaneously.
C) Multiple mutations are required to cause most forms of cancer.
D) A person gets cancer only if both of his or her parents had cancer.

Accepted Answer

The multiple hit model of cancer suggests that multiple mutations are required to cause most forms of cancer. It is unlikely that a single mutation will result in cancer, but rather a series of genetic changes must occur for cancer to develop. This is supported by the fact that cancer is often associated with the accumulation of mutations over time.