What Would Be the Most Likely Result of an Inactivating

Question

What would be the most likely result of an inactivating mutation in the progesterone receptor gene?
A)the absence of secondary sex characteristics
B)the inability of the uterus to support pregnancy
C)enlarged and hyperactive uterine endometrium
D)the absence of mammary gland development
E)release of more than one oocyte per cycle

Accepted Answer

The progesterone receptor plays a key role in preparing the uterus for pregnancy by promoting the growth of the endometrial lining and preparing it to receive a fertilized egg. An inactivating mutation in the progesterone receptor gene would therefore result in the inability of the uterus to support pregnancy. This would likely lead to infertility or recurrent miscarriages.