What is the importance of the loop of Henle dipping into the renal cortex in terrestrial vertebrates?

A)absorptive processes taking place in the loop of Henle are hormonally regulated
B)differential permeabilities of ascending and descending limbs of the loop of Henle are important in establishing an osmotic gradient
C)the loop of Henle plays an important role in detoxification
D)additional filtration takes place along the loop of Henle
E)water is reabsorbed in the ascending loop of Henle