Question 110

(Multiple Choice)

Use the following information as background for the next few questions.
Immunodeficiencies can be genetic in origin,and two examples are Bruton's agammaglobulinemia,an X-linked disorder,and DiGeorge syndrome,caused by a deletion from chromosome 22.Bruton's disorder results in underdeveloped B cells,whereas DiGeorge syndrome results in a missing or seriously underdeveloped thymus.
-Bruton's disorder will likely include


A)the failure of heavy-chain gene rearrangement in B cells.
B)the failure to incorporate CD4 receptors into cell membranes.
C)an underexpression of the gene for the β chain of the T cell receptor.
D)an underexpression of the gene for the CD8 receptor molecule.
E)the inability of the bone marrow cells to interact with MHC molecules.

Answer