What Can Proteomics Reveal That Genomics Cannot

Question

What can proteomics reveal that genomics cannot?
A)the number of genes characteristic of a species
B)the patterns of alternative splicing
C)the set of proteins present within a cell or tissue type
D)the movement of transposable elements within the genome
E)the number of short tandem repeats

Accepted Answer

Proteomics can reveal the set of proteins present within a cell or tissue type, which genomics cannot because genomics only deals with the sequence information of DNA. While genomics can predict the amino acid sequence of a protein, proteomics can confirm the presence, abundance, and modifications of proteins in a sample. Proteomics can provide information on post-translational modifications, protein-protein interactions, and the activity of proteins, which can be crucial for understanding cellular processes and disease mechanisms.