In Large-Scale,genome-Wide Association Studies in Humans Using SNPs,correlation is Sought

Question

In large-scale,genome-wide association studies in humans using SNPs,correlation is sought between
A)lengthy sequences that might be shared by most members of a population.
B)single nucleotide polymorphisms found only in persons with a particular disorder.
C)single nucleotide polymorphisms found in families with a particular intron sequence.
D)single nucleotide polymorphisms in two or more adjacent genes.
E)large inversions that displace the centromere.

Accepted Answer

In large-scale, genome-wide association studies in humans using SNPs, correlation is sought between single nucleotide polymorphisms (SNPs) found only in persons with a particular disorder. This helps identify genetic variations associated with the disease or condition being studied. Lengthy sequences shared by most members of a population, SNPs found in families with a particular intron sequence, and SNPs in adjacent genes may not be as informative in identifying disease-associated variations. Large inversions that displace the centromere are typically rare and not as relevant in this context.